Glossary

Type a term:

Breast Cancer Cell Growth in Isolated Environments

In the total absence of natural estrogen, breast cancer cells (MCF-7 cells) were able to grow and proliferate in common laboratory tubes. Further examination of the tubes demonstrated that an estrogen-mimicking chemical (p-nonyl-phenol) was leaching out of the plastic of the tube and stimulating cell growth. p-Nonyl-phenol and related compounds are commonly used in the manufacturing of plastics such as polyvinylchloride (PVC) and can easily leach from PVC pipes and packaging, contaminating foods and water [Soto et al., 1991].